中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HV121127 |
|---|---|
| 種反応性 | Human |
| アプリケーション | ELISA, FCM |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG2, kappa |
| クローンID | SAA0825 |
| 抱合 | PE |
| テスト済みアプリケーション | FCM |
| ターゲット | IL-31RA, Interleukin-31 receptor subunit alpha, IL31RA, hGLM-R, ZcytoR17, IL-31R-alpha, GPL, CRL3, Cytokine receptor-like 3, IL-31R subunit alpha, IL-31 receptor subunit alpha, Gp130-like receptor, GLM-R, Gp130-like monocyte receptor |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 関連製品 | Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10), PE |
| アクセッション番号 | Q8NI17 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Interleukin-31 receptor subunit alpha (IL31RA) is a ~82 kDa protein. Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro. _x005F_x000D_ _x005F_x000D_1. Ghilardi, N. et al. (2002) The Journal of biological chemistry 277, 16831-6. PMID: 11877449 _x005F_x000D_
_x005F_x000D_
2. Diveu, C. et al. (2003) The Journal of biological chemistry 278, 49850-9. PMID: 14504285 _x005F_x000D_
_x005F_x000D_
3. Dreuw, A. et al. (2004) The Journal of biological chemistry 279, 36112-20. PMID: 15194700 _x005F_x000D_
_x005F_x000D_
4. Diveu, C. et al. (2004) European cytokine network 15, 291-302. PMID: 15627637 _x005F_x000D_
_x005F_x000D_
5. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896 |
| 注意事項 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
Flow-cytometry using PE anti-human IL31RA antibody. U87 cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human IL31RA monoclonal antibody (Catalog: HV121127, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
