Anti-Human IL-33 Recombinant Antibody (C2_2E12) (HF543013)

Name: Anti-Human IL-33 Recombinant Antibody (C2_2E12)
Brand: abinScience
SKU: HF543013
Price: 196 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HF543013

Reactividad de especies

Human

Aplicaciones

Blocking, ELISA, WB

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG1

ID de clon

C2_2E12

Objetivo

NF-HEV, IL-1F11, C9orf26, IL-33, Interleukin-1 family member 11, IL33, Nuclear factor from high endothelial venules, NFHEV, Interleukin-33, IL1F11

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

O95760

RRID

Anti-Human IL33 Antibody (C2_2E12) (abinScience Cat# HF543013, RRID:AB_3725209)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Interleukin-33 (IL33) is a ~30 kDa protein. Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as an enhancer of polarization of alternatively activated macrophages. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury.

1. Schmitz, J. et al. (2005) Immunity 23, 479-90. PMID: 16286016

2. Kurowska-Stolarska, M. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 6469-77. PMID: 19841166

3. Komai-Koma, M. et al. (2007) European journal of immunology 37, 2779-86. PMID: 17853410

4. Moussion, C. et al. (2008) PloS one 3, e3331. PMID: 18836528

Nota

For research use only.

Imágenes