Anti-Human IL-33 Recombinant Antibody (SAA0395), APC (HF543137)

Name: Anti-Human IL-33 Recombinant Antibody (SAA0395), APC
Brand: abinScience
SKU: HF543137
Price: 256 USD
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Número de catálogo	HF543137
Reactividad de especies	Human
Aplicaciones	ELISA, FCM
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG1, lambda
ID de clon	SAA0395
Conjugación	APC
Objetivo	NF-HEV, IL-1F11, C9orf26, IL-33, Interleukin-1 family member 11, IL33, Nuclear factor from high endothelial venules, NFHEV, Interleukin-33, IL1F11
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Mouse IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
Número de acceso	O95760
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Interleukin-33 (IL33) is a ~30 kDa protein. Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as an enhancer of polarization of alternatively activated macrophages. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury. 1. Schmitz, J. et al. (2005) Immunity 23, 479-90. PMID: 16286016 2. Kurowska-Stolarska, M. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 6469-77. PMID: 19841166 3. Komai-Koma, M. et al. (2007) European journal of immunology 37, 2779-86. PMID: 17853410 4. Moussion, C. et al. (2008) PloS one 3, e3331. PMID: 18836528
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.