Anti-Human IL-33 Recombinant Antibody (SAA0395), APC (HF543137)

Name: Anti-Human IL-33 Recombinant Antibody (SAA0395), APC
Brand: abinScience
SKU: HF543137
Price: 256 USD
Availability: InStock

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Numéro de catalogue	HF543137
Reactivité des espèces	Human
Applications	ELISA, FCM
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG1, lambda
ID de clone	SAA0395
Conjugaison	APC
Cible	NF-HEV, IL-1F11, C9orf26, IL-33, Interleukin-1 family member 11, IL33, Nuclear factor from high endothelial venules, NFHEV, Interleukin-33, IL1F11
Niveau d'endotoxines	Please contact with the lab for this information.
Produits associés	Mouse IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
Numéro d'accès	O95760
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte	Interleukin-33 (IL33) is a ~30 kDa protein. Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as an enhancer of polarization of alternatively activated macrophages. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury. 1. Schmitz, J. et al. (2005) Immunity 23, 479-90. PMID: 16286016 2. Kurowska-Stolarska, M. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 6469-77. PMID: 19841166 3. Komai-Koma, M. et al. (2007) European journal of immunology 37, 2779-86. PMID: 17853410 4. Moussion, C. et al. (2008) PloS one 3, e3331. PMID: 18836528
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.