

| Número de catálogo | HV820013 | ||||
|---|---|---|---|---|---|
| Reactividad de especies | Human | ||||
| Aplicaciones | ELISA | ||||
| Especie huésped | Mouse | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG2a, kappa | ||||
| ID de clon | SAA1625 | ||||
| Objetivo | FIL1Z, IL37, Interleukin-1-related protein, IL-23, IL1F7, IL-37, IL1RP1, FIL1 zeta, IL-1X, Interleukin-23, IL-1F7, IL-1RP1, Interleukin-1 family member 7, Interleukin-37, Interleukin-1 homolog 4, Interleukin-1 zeta, IL-1H, IL-1H4, IL-1 zeta, IL1H4 | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | Q9NZH6 | ||||
| RRID | Anti-Human IL37/IL1F7 Antibody (SAA1625) (abinScience Cat# HV820013, RRID:AB_3727386) |
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| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Fondo | Interleukin-37 (IL37/IL1F7) is a ~24 kDa protein. Immune regulatory cytokine that acts as a suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. Signaling can occur via two mechanisms, intracellularly through nuclear translocation with SMAD3 and extracellularly after secretion and binding to its receptor composed of IL18R1 and IL18RAP. Suppresses, or reduces, pro-inflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation. | ||||
| Nota | For research use only. |

SDS-PAGE for Anti-Human IL37/IL1F7 Antibody (SAA1625)
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