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| カタログ番号 | HS889014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human IMMT Polyclonal Antibody (HS889014) is a rabbit polyclonal antibody detecting IMMT in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human IMMT (Ala489-Glu758). | ||||||||
| ターゲット | p87/89, Mitofilin, Mitochondrial inner membrane protein, IMMT, HMP, MICOS complex subunit MIC60, Cell proliferation-inducing gene 4/52 protein, MIC60, MINOS2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q16891 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | MICOS complex subunit MIC60 (IMMT) is a ~83 kDa protein. Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology. 1. Alkhaja, AK. et al. (2012) Molecular biology of the cell 23, 247-57. PMID: 22114354 2. Ott, C. et al. (2015) PloS one 10, e0120213. PMID: 25781180 3. Stephan, T. et al. (2020) The EMBO journal 39, e104105. PMID: 32567732 4. Hu, C. et al. (2020) Cell death & disease 11, 940. PMID: 33130824 | ||||||||
| 注意事項 | For research use only. |
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