Anti-Human IST1 Polyclonal Antibody (HX152014)

Name: Anti-Human IST1 Polyclonal Antibody
Brand: abinScience
SKU: HX152014
Price: 96 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HX152014

説明

Anti-Human IST1 Polyclonal Antibody (HX152014) is a rabbit polyclonal antibody detecting IST1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human IST1 (Met1-Glu186).

ターゲット

Putative MAPK-activating protein PM28, IST1, IST1 homolog, KIAA0174, hIST1

精製

Purified by antigen affinity column.

アクセッション番号

P53990

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

IST1 homolog is a ~39 kDa protein. ESCRT-III-like protein involved in cytokinesis, nuclear envelope reassembly and endosomal tubulation. Is required for efficient abscission during cytokinesis. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing. Recruited to the reforming nuclear envelope (NE) during anaphase by LEMD2.

1. Bajorek, M. et al. (2009) Molecular biology of the cell 20, 1360-73. PMID: 19129479

2. Vietri, M. et al. (2015) Nature 522, 231-5. PMID: 26040712

3. Gu, M. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, E2166-E2175. PMID: 28242692

4. Agromayor, M. et al. (2009) Molecular biology of the cell 20, 1374-87. PMID: 19129480

5. Allison, R. et al. (2013) The Journal of cell biology 202, 527-43. PMID: 23897888

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-Human IST1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-Human IST1 Polyclonal Antibody (HX152014)

概要

イメージ

参考文献

データシート

SDS

クイックアクセス

お問い合わせ