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Anti-Human JADE1 Polyclonal Antibody (HA939014)

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Aperçu
Numéro de catalogueHA939014
Description
Anti-Human JADE1 Polyclonal Antibody (HA939014) is a rabbit polyclonal antibody detecting JADE1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman, Mouse
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human JADE1 (Gly217-Ser363).
Cible KIAA1807, Jade family PHD finger protein 1, JADE1, PHD finger protein 17, Protein Jade-1, PHF17
Purification Purified by antigen affinity column.
Numéro d'accès Q6IE81
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Protein Jade-1 (JADE1) is a ~95 kDa protein. Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation. May also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor.

1. Doyon, Y. et al. (2006) Molecular cell 21, 51-64. PMID: 16387653
2. Saksouk, N. et al. (2009) Molecular cell 33, 257-65. PMID: 19187766
3. Miotto, B. et al. (2010) Molecular cell 37, 57-66. PMID: 20129055
4. Lalonde, ME. et al. (2013) Genes & development 27, 2009-24. PMID: 24065767
5. Panchenko, MV. et al. (2004) The Journal of biological chemistry 279, 56032-41. PMID: 15502158
6. Zhou, MI. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 11035-40. PMID: 16046545
7. Borgal, L. et al. (2012) The Journal of biological chemistry 287, 25370-80. PMID: 22654112
Note For research use only.
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Reférences
Fiche technique
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human JADE1 Polyclonal Antibody

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