中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HP669013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1837 | ||||
| ターゲット | JAM-3, JAM-C, JAM-2, Junctional adhesion molecule 3, Junctional adhesion molecule C, sJAM-C, JAM3 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q9BX67 | ||||
| RRID | Anti-Human JAM3 Antibody (SAA1837) (abinScience Cat# HP669013, RRID:AB_3727600) |
||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||
| 製品使用情報 |
| ||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Junctional adhesion molecule C (JAM3) is a ~35 kDa protein. Junctional adhesion protein that mediates heterotypic cell-cell interactions with its cognate receptor JAM2 to regulate different cellular processes. Plays a role in homing and mobilization of hematopoietic stem and progenitor cells within the bone marrow. At the surface of bone marrow stromal cells, it contributes to the retention of the hematopoietic stem and progenitor cells expressing JAM3. Plays a central role in leukocytes extravasation by facilitating transmigration through the endothelium. Plays a role in spermatogenesis where JAM2 and JAM3, which are respectively expressed by Sertoli and germ cells, mediate an interaction between both cell types and play an essential role in the anchorage of germ cells onto Sertoli cells and the assembly of cell polarity complexes during spermatid differentiation. 1. Arrate, MP. et al. (2001) The Journal of biological chemistry 276, 45826-32. PMID: 11590146 2. Liang, TW. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 1618-26. PMID: 11823489 3. Arcangeli, ML. et al. (2014) Stem cells (Dayton, Ohio) 32, 1043-54. PMID: 24357068 4. Santoso, S. et al. (2002) The Journal of experimental medicine 196, 679-91. PMID: 12208882 5. Zen, K. et al. (2004) Molecular biology of the cell 15, 3926-37. PMID: 15194813 6. Akawi, NA. et al. (2013) Human mutation 34, 498-505. PMID: 23255084 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human JAM3 Antibody (SAA1837)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
