Anti-Human KAT2B Polyclonal Antibody (HA390014)

Name: Anti-Human KAT2B Polyclonal Antibody
Brand: abinScience
SKU: HA390014
Price: 168 USD
Availability: InStock

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Каталожный номер

HA390014

Описание

Anti-Human KAT2B Polyclonal Antibody (HA390014) is a rabbit polyclonal antibody detecting KAT2B in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human KAT2B (Leu352-Lys832).

Цель

P300/CBP-associated factor, P/CAF, Histone acetylase PCAF, Lysine acetyltransferase 2B, Spermidine acetyltransferase KAT2B, PCAF, Histone acetyltransferase KAT2B, KAT2B, Histone acetyltransferase PCAF

Очистка

Purified by antigen affinity column.

Номер доступа

Q92831

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Histone acetyltransferase KAT2B is a ~93 kDa protein. Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Has a a strong preference for acetylation of H3 at 'Lys-9' (H3K9ac). Also acetylates non-histone proteins, such as ACLY, MAPRE1/EB1, PLK4, RRP9/U3-55K and TBX5. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A.

1. Ogryzko, VV. et al. (1996) Cell 87, 953-9. PMID: 8945521

2. Jin, Q. et al. (2011) The EMBO journal 30, 249-62. PMID: 21131905

3. Martínez-Balbás, MA. et al. (2000) The EMBO journal 19, 662-71. PMID: 10675335

4. Xia, P. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 16564-9. PMID: 23001180

5. Lin, R. et al. (2013) Molecular cell 51, 506-518. PMID: 23932781

6. Chen, S. et al. (2016) Nature communications 7, 10734. PMID: 26867678

7. Fournier, M. et al. (2016) Nature communications 7, 13227. PMID: 27796307

8. Ghosh, TK. et al. (2018) Journal of molecular and cellular cardiology 114, 185-198. PMID: 29174768

9. Zhang, W. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 9855-60. PMID: 9707565

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human KAT2B Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

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Anti-Human KAT2B Polyclonal Antibody (HA390014)

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