中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HA390024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human KAT2B Polyclonal Antibody (HA390024) is a rabbit polyclonal antibody detecting KAT2B. Suitable for Mouse and Human.
Highlights
|
||||||||
| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human KAT2B (Asn651-Lys818). | ||||||||
| ターゲット | EC:2.3.1.48, EC:2.3.1.57, Histone acetylase PCAF, Histone acetyltransferase KAT2B, Histone acetyltransferase PCAF, KAT2B, Lysine acetyltransferase 2B, P/CAF, P300/CBP-associated factor, PCAF, Spermidine acetyltransferase KAT2B | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q92831 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 背景 | Histone acetyltransferase KAT2B is a ~93 kDa protein. Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Has a a strong preference for acetylation of H3 at 'Lys-9' (H3K9ac). Also acetylates non-histone proteins, such as ACLY, MAPRE1/EB1, PLK4, RRP9/U3-55K and TBX5. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. 1. Ogryzko, VV. et al. (1996) Cell 87, 953-9. PMID: 8945521 2. Jin, Q. et al. (2011) The EMBO journal 30, 249-62. PMID: 21131905 3. Martínez-Balbás, MA. et al. (2000) The EMBO journal 19, 662-71. PMID: 10675335 4. Xia, P. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 16564-9. PMID: 23001180 5. Lin, R. et al. (2013) Molecular cell 51, 506-518. PMID: 23932781 6. Chen, S. et al. (2016) Nature communications 7, 10734. PMID: 26867678 7. Fournier, M. et al. (2016) Nature communications 7, 13227. PMID: 27796307 8. Ghosh, TK. et al. (2018) Journal of molecular and cellular cardiology 114, 185-198. PMID: 29174768 9. Zhang, W. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 9855-60. PMID: 9707565 | ||||||||
| 注意事項 | For research use only |
お問い合わせ
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
