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| カタログ番号 | HA290014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human KCNIP4 Polyclonal Antibody (HA290014) is a rabbit polyclonal antibody detecting KCNIP4. Suitable for Rat, Mouse, and Human.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human KCNIP4 (Ser56-Ile250). | ||||||||
| ターゲット | A-type potassium channel modulatory protein 4, CALP, Calsenilin-like protein, KCHIP4, KCNIP4, KChIP4, Kv channel-interacting protein 4, Potassium channel-interacting protein 4 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q6PIL6 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Kv channel-interacting protein 4 (KCNIP4) is a ~28 kDa protein. Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. Modulates KCND3/Kv4.3 currents. Isoform 4 does not increase KCND2 expression at the cell membrane. Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane. 1. Morohashi, Y. et al. (2002) The Journal of biological chemistry 277, 14965-75. PMID: 11847232 2. Jerng, HH. et al. (2008) The Journal of biological chemistry 283, 36046-59. PMID: 18957440 3. Tang, YQ. et al. (2013) The Journal of biological chemistry 288, 14727-41. PMID: 23576435 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-KCNIP4 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate
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