Anti-Human KCNK9 Recombinant Antibody (SAA1716) (HV232013)

Name: Anti-Human KCNK9 Recombinant Antibody (SAA1716)
Brand: abinScience
SKU: HV232013
Price: 196 USD
Availability: InStock

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Спецификация:

50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HV232013

Реактивность видов

Human

Применения

ELISA

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a, kappa

ID клона

SAA1716

Цель

TASK3, KCNK9, Acid-sensitive potassium channel protein TASK-3, Potassium channel subfamily K member 9, Two pore K(+) channel KT3.2, TWIK-related acid-sensitive K(+) channel 3, Two pore potassium channel KT3.2

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

Q9NPC2

RRID

Anti-Human KCNK9 Antibody (SAA1716) (abinScience Cat# HV232013, RRID:AB_3727477)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Potassium channel subfamily K member 9 (KCNK9) is a ~42 kDa protein. K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens the gate. Changes ion selectivity and becomes permeable to Na(+) ions in response to extracellular acidification. Protonation of the pH sensor His-98 stabilizes C-type inactivation conformation likely converting the channel from outward K(+)-conducting, to inward Na(+)-conducting to nonconductive state. Homo- and heterodimerizes to form functional channels with distinct regulatory and gating properties.

1. Chapman, CG. et al. (2000) Brain research. Molecular brain research 82, 74-83. PMID: 11042359

2. Vega-Saenz de Miera, E. et al. (2001) Journal of neurophysiology 86, 130-42. PMID: 11431495

3. Schewe, M. et al. (2016) Cell 164, 937-49. PMID: 26919430

4. Lin, H. et al. (2024) Proceedings of the National Academy of Sciences of the United States of America 121, e2320345121. PMID: 38630723

5. Ma, L. et al. (2012) The Journal of biological chemistry 287, 37145-53. PMID: 22948150

6. Plant, LD. et al. (2012) Science signaling 5, ra84. PMID: 23169818

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human KCNK9 Antibody (SAA1716)

Ссылки

Даташит

Anti-Human KCNK9 Recombinant Antibody (SAA1716).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа