

| Numéro de catalogue | HP303013 | ||||
|---|---|---|---|---|---|
| Reactivité des espèces | Human | ||||
| Applications | ELISA, IF, IP | ||||
| Espèce hôte | Mouse | ||||
| Clonalité | Monoclonal | ||||
| Isotype | IgG1 | ||||
| ID de clone | SAA0201 | ||||
| Cible | KDM2A, CXXC-type zinc finger protein 8, FBXL11, JHDM1A, FBL7, KIAA1004, F-box protein FBL7, Lysine-specific demethylase 2A, FBL11, [Histone-H3]-lysine-36 demethylase 1A, F-box protein Lilina, JmjC domain-containing histone demethylation protein 1A, F-box/LRR-repeat protein 11, CXXC8, F-box and leucine-rich repeat protein 11 | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | Q9Y2K7 | ||||
| RRID | Anti-Human KDM2A IP Antibody (SAA0201) (abinScience Cat# HP303013, RRID:AB_3729735) |
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| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Contexte | Lysine-specific demethylase 2A (KDM2A) is a ~132 kDa protein. Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. 1. Reischl, S. et al. (2015) Journal of biological rhythms 30, 291-301. PMID: 26037310 | ||||
| Note | For research use only. | ||||
| Isotype Control | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207) |

SDS-PAGE for Anti-Human KDM2A IP Antibody (SAA0201)
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