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| カタログ番号 | HP303013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA, IF, IP | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG1 | ||||
| クローンID | SAA0201 | ||||
| ターゲット | KDM2A, CXXC-type zinc finger protein 8, FBXL11, JHDM1A, FBL7, KIAA1004, F-box protein FBL7, Lysine-specific demethylase 2A, FBL11, [Histone-H3]-lysine-36 demethylase 1A, F-box protein Lilina, JmjC domain-containing histone demethylation protein 1A, F-box/LRR-repeat protein 11, CXXC8, F-box and leucine-rich repeat protein 11 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q9Y2K7 | ||||
| RRID | Anti-Human KDM2A IP Antibody (SAA0201) (abinScience Cat# HP303013, RRID:AB_3729735) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Lysine-specific demethylase 2A (KDM2A) is a ~132 kDa protein. Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. 1. Reischl, S. et al. (2015) Journal of biological rhythms 30, 291-301. PMID: 26037310 | ||||
| 注意事項 | For research use only. | ||||
| Isotype Control | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207) |
SDS-PAGE for Anti-Human KDM2A IP Antibody (SAA0201)
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