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Anti-Human KDM4B IP Recombinant Antibody (SAA0205) (HF804013)

Anti-Human KDM4B IP Recombinant Antibody (SAA0205)
Anti-Human KDM4B IP Recombinant Antibody (SAA0205)
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Aperçu
Numéro de catalogueHF804013
Reactivité des espècesHuman
ApplicationsELISA, IF, IP
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a
ID de cloneSAA0205
Cible Jumonji domain-containing protein 2B, KDM4B, JmjC domain-containing histone demethylation protein 3B, JHDM3B, JMJD2B, Lysine-specific demethylase 4B, [histone H3]-trimethyl-L-lysine(9) demethylase 4B, KIAA0876
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès O94953
RRID Anti-Human KDM4B IP Antibody (SAA0205) (abinScience Cat# HF804013, RRID:AB_3729739)
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Lysine-specific demethylase 4B (KDM4B) is a ~121 kDa protein. Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. Plays a critical role in the development of the central nervous system (CNS).

1. Whetstine, JR. et al. (2006) Cell 125, 467-81. PMID: 16603238
2. Tumber, A. et al. (2017) Cell chemical biology 24, 371-380. PMID: 28262558
Note For research use only.
Images
  • Anti-Human KDM4B IP Recombinant Antibody (SAA0205)

    SDS-PAGE

    SDS-PAGE for Anti-Human KDM4B IP Antibody (SAA0205)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
Recommandation

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