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| カタログ番号 | HF804013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA, IF, IP | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a | ||||
| クローンID | SAA0205 | ||||
| ターゲット | Jumonji domain-containing protein 2B, KDM4B, JmjC domain-containing histone demethylation protein 3B, JHDM3B, JMJD2B, Lysine-specific demethylase 4B, [histone H3]-trimethyl-L-lysine(9) demethylase 4B, KIAA0876 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | O94953 | ||||
| RRID | Anti-Human KDM4B IP Antibody (SAA0205) (abinScience Cat# HF804013, RRID:AB_3729739) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Lysine-specific demethylase 4B (KDM4B) is a ~121 kDa protein. Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. Plays a critical role in the development of the central nervous system (CNS). 1. Whetstine, JR. et al. (2006) Cell 125, 467-81. PMID: 16603238 2. Tumber, A. et al. (2017) Cell chemical biology 24, 371-380. PMID: 28262558 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human KDM4B IP Antibody (SAA0205)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
