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Anti-Human KHDRBS1 Polyclonal Antibody (HC692014)

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Aperçu
Numéro de catalogueHC692014
Description
Anti-Human KHDRBS1 Polyclonal Antibody (HC692014) is a rabbit polyclonal antibody detecting KHDRBS1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human KHDRBS1 (Lys111-Gly276).
Cible p21 Ras GTPase-activating protein-associated p62, GAP-associated tyrosine phosphoprotein p62, KH domain-containing, RNA-binding, signal transduction-associated protein 1, SAM68, p68, Sam68, KHDRBS1, Src-associated in mitosis 68 kDa protein
Purification Purified by antigen affinity column.
Numéro d'accès Q07666
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

KH domain-containing, RNA-binding, signal transduction-associated protein 1 (KHDRBS1) is a ~48 kDa protein. Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.

1. Rajanala, K. et al. (2012) PloS one 7, e29921. PMID: 22253824
2. Nakka, KK. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, E3374-83. PMID: 26080397
3. Paronetto, MP. et al. (2007) The Journal of cell biology 176, 929-39. PMID: 17371836
4. Pedrotti, S. et al. (2010) The EMBO journal 29, 1235-47. PMID: 20186123
Note For research use only.
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Reférences
Fiche technique
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human KHDRBS1 Polyclonal Antibody

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