

| Número de catálogo | HP704014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human KIF2C (Asn229-Ser589). | ||||||||
| Objetivo | Mitotic centromere-associated kinesin, Kinesin-like protein 6, KIF2C, Kinesin-like protein KIF2C, KNSL6, MCAK | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q99661 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Kinesin-like protein KIF2C is a ~81 kDa protein. In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment. 1. Tanenbaum, ME. et al. (2011) Current biology : CB 21, 1356-65. PMID: 21820309 2. Bakhoum, SF. et al. (2009) Nature cell biology 11, 27-35. PMID: 19060894 3. Shrestha, RL. et al. (2013) Current biology : CB 23, 1514-26. PMID: 23891108 | ||||||||
| Nota | For research use only. |

Western blot analysis was performed using anti-KIF2C polyclonal antibody at 1μg/ml on various samples.
Lane 1: K562 cell lysate
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