Anti-Human KPTN Polyclonal Antibody (HD506014)

Name: Anti-Human KPTN Polyclonal Antibody
Brand: abinScience
SKU: HD506014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

Número:

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SDS

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Número de catálogo

HD506014

Descripción

Anti-Human KPTN Polyclonal Antibody (HD506014) is a rabbit polyclonal antibody detecting KPTN. Suitable for Human.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human KPTN (Met1-Ser396).

Objetivo

Actin-associated protein 2E4, KICSTOR complex protein kaptin, KPTN

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

Q9Y664

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Fondo

KICSTOR complex protein kaptin (KPTN) is a ~48 kDa protein. As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-Human KPTN Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human KPTN Polyclonal Antibody (HD506014)

Vista general

Imágenes

Referencias

Datasheet

SDS