

| Numéro de catalogue | HW429014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human KRT2 Polyclonal Antibody (HW429014) is a rabbit polyclonal antibody detecting KRT2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human KRT2 (Asn342-Leu495). | ||||||||
| Cible | Keratin, type II cytoskeletal 2 epidermal, Cytokeratin-2e, CK-2e, Epithelial keratin-2e, Keratin-2 epidermis, Keratin-2e, K2e, Type-II keratin Kb2, KRT2, KRT2A, KRT2E | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P35908 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Keratin, type II cytoskeletal 2 epidermal (KRT2) is a ~65 kDa protein. Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. Required for maintenance of corneocytes and keratin filaments in suprabasal keratinocytes in the epidermis of the ear, potentially via moderation of expression and localization of keratins and their partner proteins. Plays a role in the establishment of the epidermal barrier on plantar skin. 1. Collin, C. et al. (1992) Experimental cell research 202, 132-41. PMID: 1380918 2. Bloor, BK. et al. (2003) The American journal of pathology 162, 963-75. PMID: 12598329 | ||||||||
| Note | For research use only. |
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