

| Numéro de catalogue | HP549013 | ||||
|---|---|---|---|---|---|
| Reactivité des espèces | Human | ||||
| Applications | ELISA, IF, IP | ||||
| Espèce hôte | Mouse | ||||
| Clonalité | Monoclonal | ||||
| Isotype | IgG1 | ||||
| ID de clone | SAA0263 | ||||
| Cible | L(3)mbt-like, H-l(3)mbt protein, H-l(3)mbt, Lethal(3)malignant brain tumor-like protein 1, L3MBT, L3MBTL1, KIAA0681, L3MBTL, L(3)mbt protein homolog | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | Q9Y468 | ||||
| RRID | Anti-Human L3MBTL1 IP Antibody (SAA0263) (abinScience Cat# HP549013, RRID:AB_3729797) |
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| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Contexte | Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1) is a ~92 kDa protein. Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, thereby acting as a 'reader' of a network of post-translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/H1-4 at 'Lys-26' (H1bK26me1 and H1bK26me2) and histone H4 at 'Lys-20' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription. Recognizes and binds p53/TP53 monomethylated at 'Lys-382', leading to repress p53/TP53-target genes. Also recognizes and binds RB1/RB monomethylated at 'Lys-860'. Participates in the ETV6-mediated repression. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human L3MBTL1 IP Antibody (SAA0263)
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