Anti-Human LETM1 Polyclonal Antibody (HF870014)

Name: Anti-Human LETM1 Polyclonal Antibody
Brand: abinScience
SKU: HF870014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HF870014

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human LETM1 (Leu231-Thr426).

Objetivo

LETM1, Leucine zipper-EF-hand-containing transmembrane protein 1, Mitochondrial proton/calcium exchanger protein

Purificación

Purified by antigen affinity column.

Número de acceso

O95202

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Mitochondrial proton/calcium exchanger protein (LETM1) is a ~83 kDa protein. Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport. Mediates proton-dependent calcium efflux from mitochondrion. Also functions as an electroneutral mitochondrial proton/potassium exchanger. Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain. Required for the maintenance of the tubular shape and cristae organization.

1. Tamai, S. et al. (2008) Journal of cell science 121, 2588-600. PMID: 18628306

2. Jiang, D. et al. (2009) Science (New York, N.Y.) 326, 144-7. PMID: 19797662

3. Tsai, MF. et al. (2014) The Journal of general physiology 143, 67-73. PMID: 24344246

4. De Marchi, U. et al. (2014) The Journal of biological chemistry 289, 20377-85. PMID: 24898248

5. Huang, E. et al. (2017) Nature communications 8, 1399. PMID: 29123128

6. Nakamura, S. et al. (2020) Communications biology 3, 99. PMID: 32139798

7. Kaiyrzhanov, R. et al. (2022) American journal of human genetics 109, 1692-1712. PMID: 36055214

8. Austin, S. et al. (2022) EMBO reports 23, e54978. PMID: 36321428

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human LETM1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo