Anti-Human LGR4/GPR48 Recombinant Antibody (SAA0107) (HV980107)

Name: Anti-Human LGR4/GPR48 Recombinant Antibody (SAA0107)
Brand: abinScience
SKU: HV980107
Price: 191 USD
Availability: InStock

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Vista general

Número de catálogo	HV980107
Reactividad de especies	Human
Aplicaciones	ELISA, FCM, IHC, WB
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1
ID de clon	SAA0107
Objetivo	GPR48, Leucine-rich repeat-containing G-protein coupled receptor 4, LGR4, G-protein coupled receptor 48, RHJ50601
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q9BXB1
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Leucine-rich repeat-containing G-protein coupled receptor 4 (LGR4) is a ~104 kDa protein. Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Its function as activator of the Wnt signaling pathway is required for the development of various organs, including liver, kidney, intestine, bone, reproductive tract and eye. May also act as a receptor for norrin (NDP), such results however require additional confirmation in vivo.
Nota	For research use only.

Imágenes

Bioactivity

SEC-HPLC detection for Anti-Human LGR4 Antibody (ABS0206).

Referencias

Datasheet

Anti-Human LGR4/GPR48 Recombinant Antibody (SAA0107).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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