Anti-Human LGR4/GPR48 Recombinant Antibody (SAA0107) (HV980107)

Name: Anti-Human LGR4/GPR48 Recombinant Antibody (SAA0107)
Brand: abinScience
SKU: HV980107
Price: 191 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HV980107
Reactivité des espèces	Human
Applications	ELISA, FCM, IHC, WB
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1
ID de clone	SAA0107
Cible	GPR48, Leucine-rich repeat-containing G-protein coupled receptor 4, LGR4, G-protein coupled receptor 48, RHJ50601
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q9BXB1
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	Leucine-rich repeat-containing G-protein coupled receptor 4 (LGR4) is a ~104 kDa protein. Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Its function as activator of the Wnt signaling pathway is required for the development of various organs, including liver, kidney, intestine, bone, reproductive tract and eye. May also act as a receptor for norrin (NDP), such results however require additional confirmation in vivo.
Note	For research use only.

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Bioactivity

SEC-HPLC detection for Anti-Human LGR4 Antibody (ABS0206).

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Anti-Human LGR4/GPR48 Recombinant Antibody (SAA0107).pdf

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