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Anti-Human LMNB1 Polyclonal Antibody (HB096024)

Anti-Human LMNB1 Polyclonal Antibody
Anti-Human LMNB1 Polyclonal Antibody
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  • 20ug
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  • 100ug
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Vista general
Número de catálogoHB096024
Descripción
Anti-Human LMNB1 Polyclonal Antibody (HB096024) is a rabbit polyclonal antibody detecting LMNB1 in ELISA, IHC, WB. Suitable for Human, Mus musculus, Rattus norvegicus, and Gallus gallus.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human LMNB1 (Ala426-Glu558).
Objetivo LMNB1
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso P20700
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosLamin-B1, LMNB1, LMN2, LMNB
Fondo

Lamin-B1 (LMNB1) is a ~66 kDa protein. Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane. Lamins provide a framework for the nuclear envelope, bridging the nuclear envelope and chromatin, thereby playing an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. The structural integrity of the lamina is strictly controlled by the cell cycle, as seen by the disintegration and formation of the nuclear envelope in prophase and telophase, respectively.

1. Pedroso, JL. et al. (2017) Journal of the neurological sciences 379, 249-252. PMID: 28716252
2. Cristofoli, F. et al. (2020) American journal of human genetics 107, 753-762. PMID: 32910914
Nota For research use only.
Imágenes
  • Anti-Human LMNB1 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-LMNB1 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Hela cell lysate
    Lane 2: K562 cell lysate
    Lane 3: HepG2 cell lysate
    Lane 4: NIH3T3 cell lysate
    Lane 5: Mouse spleen lysate
    Lane 6: Rat spleen lysate
    Lane 7: Rat testis lysate

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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