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| カタログ番号 | HB096024 | ||||||||
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| 説明 |
Anti-Human LMNB1 Polyclonal Antibody (HB096024) is a rabbit polyclonal antibody detecting LMNB1 in ELISA, IHC, WB. Suitable for Human, Mus musculus, Rattus norvegicus, and Gallus gallus.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human LMNB1 (Ala426-Glu558). | ||||||||
| ターゲット | LMNB1 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P20700 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 別名 | Lamin-B1, LMNB1, LMN2, LMNB | ||||||||
| 背景 | Lamin-B1 (LMNB1) is a ~66 kDa protein. Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane. Lamins provide a framework for the nuclear envelope, bridging the nuclear envelope and chromatin, thereby playing an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. The structural integrity of the lamina is strictly controlled by the cell cycle, as seen by the disintegration and formation of the nuclear envelope in prophase and telophase, respectively. 1. Pedroso, JL. et al. (2017) Journal of the neurological sciences 379, 249-252. PMID: 28716252 2. Cristofoli, F. et al. (2020) American journal of human genetics 107, 753-762. PMID: 32910914 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-LMNB1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: K562 cell lysate
Lane 3: HepG2 cell lysate
Lane 4: NIH3T3 cell lysate
Lane 5: Mouse spleen lysate
Lane 6: Rat spleen lysate
Lane 7: Rat testis lysate
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