Anti-Human LMNB2 Polyclonal Antibody (HX984014)

Name: Anti-Human LMNB2 Polyclonal Antibody
Brand: abinScience
SKU: HX984014
Price: 96 USD
Availability: InStock

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Vista general

Número de catálogo

HX984014

Descripción

Anti-Human LMNB2 Polyclonal Antibody (HX984014) is a rabbit polyclonal antibody detecting LMNB2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human LMNB2 (Gly461-Ser581).

Objetivo

LMN2, LMNB2, Lamin-B2

Purificación

Purified by antigen affinity column.

Número de acceso

Q03252

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Lamin-B2 (LMNB2) is a ~69 kDa protein. Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane. Lamins provide a framework for the nuclear envelope, bridging the nuclear envelope and chromatin, thereby playing an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. The structural integrity of the lamina is strictly controlled by the cell cycle, as seen by the disintegration and formation of the nuclear envelope in prophase and telophase, respectively.

1. Parry, DA. et al. (2021) Genetics in medicine : official journal of the American College of Medical Genetics 23, 408-414. PMID: 33033404

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-LMNB2 polyclonal antibody at 1μg/ml on various samples.
Lane 1: HepG2 cell lysate
Lane 2: Raji cell lysate
Lane 3: Jurkat cell lysate
Lane 4: Hela cell lysate
Lane 5: 293T cell lysate
Lane 6: MCF-7 cell lysate