Anti-Human PLA2G7/PAF-AH/Lp-PLA2 Recombinant Antibody (SAA1765) (HC293013)

Name: Anti-Human PLA2G7/PAF-AH/Lp-PLA2 Recombinant Antibody (SAA1765)
Brand: abinScience
SKU: HC293013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HC293013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1765

Cible

Platelet-activating factor acetylhydrolase, PAFAH, PAF 2-acylhydrolase, PAF acetylhydrolase, 2-acetyl-1-alkylglycerophosphocholine esterase, 1-alkyl-2-acetylglycerophosphocholine esterase, LDL-PLA(2), LDL-associated phospholipase A2, PLA2G7, Group-VIIA phospholipase A2, gVIIA-PLA2

Niveau d'endotoxines

< 10 EU/mg

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q13093

RRID

Anti-Human Lp-PLA2/PLA2G7/PAF-AH Antibody (SAA1765) (abinScience Cat# HC293013, RRID:AB_3727526)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Platelet-activating factor acetylhydrolase (Lp-PLA2/PLA2G7) is a ~50 kDa protein. Lipoprotein-associated calcium-independent phospholipase A2 involved in phospholipid catabolism during inflammatory and oxidative stress response. At the lipid-aqueous interface, hydrolyzes the ester bond of fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity). Specifically targets phospholipids with a short-chain fatty acyl group at sn-2 position. Can hydrolyze phospholipids with long fatty acyl chains, only if they carry oxidized functional groups. Hydrolyzes and inactivates platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine), a potent pro-inflammatory signaling lipid that acts through PTAFR on various innate immune cells.

1. Stafforini, DM. et al. (1999) The Journal of biological chemistry 274, 7018-24. PMID: 10066756

2. Stafforini, DM. et al. (2006) The Journal of biological chemistry 281, 4616-23. PMID: 16371369

3. Kriska, T. et al. (2007) The Journal of biological chemistry 282, 100-8. PMID: 17090529

4. Stremler, KE. et al. (1991) The Journal of biological chemistry 266, 11095-103. PMID: 2040620

5. Tjoelker, LW. et al. (1995) Nature 374, 549-53. PMID: 7700381

6. Tew, DG. et al. (1996) Arteriosclerosis, thrombosis, and vascular biology 16, 591-9. PMID: 8624782

7. Min, JH. et al. (1999) Biochemistry 38, 12935-42. PMID: 10504265

9. Gardner, AA. et al. (2008) The Journal of biological chemistry 283, 17099-106. PMID: 18434304

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human Lp-PLA2/PLA2G7/PAF-AH Antibody (SAA1765)

Reférences

Fiche technique

Anti-Human PLA2G7/PAF-AH/Lp-PLA2 Recombinant Antibody (SAA1765).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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