

| Numéro de catalogue | HD601014 | ||||||||
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| Description |
Anti-Human LRIF1 Polyclonal Antibody (HD601014) is a rabbit polyclonal antibody detecting LRIF1. Suitable for Human.
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human LRIF1 (His190-Asn311). | ||||||||
| Cible | C1orf103, HBiX1, HP1-binding protein enriched in inactive X chromosome protein 1, LRIF1, Ligand-dependent nuclear receptor-interacting factor 1, RIF1, Receptor-interacting factor 1 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q5T3J3 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) is a ~84 kDa protein. Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin. Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases. Also required for silencing of the DUX4 locus in somatic cells. 1. Nozawa, RS. et al. (2013) Nature structural & molecular biology 20, 566-73. PMID: 23542155 2. Li, HJ. et al. (2007) Journal of cellular biochemistry 102, 1021-35. PMID: 17455211 3. Hamanaka, K. et al. (2020) Neurology 94, e2441-e2447. PMID: 32467133 | ||||||||
| Note | For research use only |
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