Anti-Human LTK Recombinant Antibody (SAA1618) (HB966013)

Name: Anti-Human LTK Recombinant Antibody (SAA1618)
Brand: abinScience
SKU: HB966013
Price: 196 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HB966013

Reactividad de especies

Human

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

SAA1618

Objetivo

TYK1, Leukocyte tyrosine kinase receptor, LTK, Protein tyrosine kinase 1

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P29376

RRID

Anti-Human LTK Antibody (SAA1618) (abinScience Cat# HB966013, RRID:AB_3727379)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Leukocyte tyrosine kinase receptor (LTK) is a ~91 kDa protein. Receptor with a tyrosine-protein kinase activity. Following activation by ALKAL1 or ALKAL2 ligands at the cell surface, transduces an extracellular signal into an intracellular response. Ligand-binding to the extracellular domain induces tyrosine kinase activation, leading to activation of the mitogen-activated protein kinase (MAPK) pathway. Phosphorylates almost exclusively at the first tyrosine of the Y-x-x-x-Y-Y motif. The exact function of this protein is not known; studies with chimeric proteins demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival.

1. Honda, H. et al. (1999) Oncogene 18, 3821-30. PMID: 10445845

2. Farhan, H. et al. (2010) The Journal of cell biology 189, 997-1011. PMID: 20548102

3. Reshetnyak, AV. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, 8340-8345. PMID: 30061385

4. De Munck, S. et al. (2021) Nature 600, 143-147. PMID: 34646012

5. Yamada, S. et al. (2008) Neuroreport 19, 1733-8. PMID: 18849880

6. Ueno, H. et al. (1997) Oncogene 14, 3067-72. PMID: 9223670

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human LTK Antibody (SAA1618)

Referencias

Datasheet

Anti-Human LTK Recombinant Antibody (SAA1618).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo