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| カタログ番号 | HV236014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human LYVE1 Polyclonal Antibody (HV236014) is a rabbit polyclonal antibody detecting LYVE1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human LYVE1 (Arg26-Ser131). | ||||||||
| ターゲット | Cell surface retention sequence-binding protein 1, XLKD1, LYVE-1, Hyaluronic acid receptor, Extracellular link domain-containing protein 1, CRSBP-1, LYVE1, CRSBP1, HAR, Lymphatic vessel endothelial hyaluronic acid receptor 1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9Y5Y7 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE1) is a ~35 kDa protein. Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. Binds to pericelluar hyaluronan matrices deposited on the surface of leukocytes and facilitates cell adhesion and migration through lymphatic endothelium. 1. Banerji, S. et al. (1999) The Journal of cell biology 144, 789-801. PMID: 10037799 2. Lawrance, W. et al. (2016) The Journal of biological chemistry 291, 8014-30. PMID: 26823460 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-LYVE1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Rat brain lysate
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