

| Número de catálogo | HP963014 | ||||||||
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| Descripción |
Anti-Human MACROH2A2 Polyclonal Antibody (HP963014) is a rabbit polyclonal antibody detecting MACROH2A2 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human MACROH2A2 (Gly182-Lys372). | ||||||||
| Objetivo | Histone macroH2A2, H2AFY2, Core histone macro-H2A.2, mH2A2, MACROH2A2 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9P0M6 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Core histone macro-H2A.2 (MACROH2A2) is a ~40 kDa protein. Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation. | ||||||||
| Nota | For research use only. |
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