Anti-Human NHLRC1 Polyclonal Antibody (HA130014)

Name: Anti-Human NHLRC1 Polyclonal Antibody
Brand: abinScience
SKU: HA130014
Price: 168 USD
Availability: InStock

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Prix(USD) : --

Spécification :

50ug
100ug

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HA130014

Description

Anti-Human Malin Polyclonal Antibody (HA130014) is a rabbit polyclonal antibody detecting Malin. Suitable for Human.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human Malin (Gly112-Gly395).

Cible

E3 ubiquitin-protein ligase NHLRC1, EC:2.3.2.27, EPM2B, Malin, NHL repeat-containing protein 1, NHLRC1, RING-type E3 ubiquitin transferase NHLRC1

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Purified by antigen affinity column.

Numéro d'accès

Q6VVB1

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

E3 ubiquitin-protein ligase NHLRC1 (Malin) is a ~42 kDa protein. E3 ubiquitin-protein ligase. Together with the phosphatase EPM2A/laforin, appears to be involved in the clearance of toxic polyglucosan and protein aggregates via multiple pathways. In complex with EPM2A/laforin and HSP70, suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system (UPS). Ubiquitinates the glycogen-targeting protein phosphatase subunits PPP1R3C/PTG and PPP1R3D in a laforin-dependent manner and targets them for proteasome-dependent degradation, thus decreasing glycogen accumulation. Polyubiquitinates EPM2A/laforin and ubiquitinates AGL and targets them for proteasome-dependent degradation.

Note

For research use only

Images

Western blot

Western blot analysis was performed using anti-NHLRC1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate

Reférences

Fiche technique

Anti-Human NHLRC1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human NHLRC1 Polyclonal Antibody (HA130014)

Aperçu

Images

Reférences

Fiche technique

SDS