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Anti-Human MAP1B Polyclonal Antibody (HW426014)

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Anti-Human MAP1B Polyclonal Antibody
Anti-Human MAP1B Polyclonal Antibody
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Aperçu
Numéro de catalogueHW426014
Description
Anti-Human MAP1B Polyclonal Antibody (HW426014) is a rabbit polyclonal antibody detecting MAP1B in ELISA, IHC, WB. Suitable for Rattus norvegicus, Mus musculus, and Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human MAP1B (Lys414-Glu567).
Cible MAP1B
Purification Purified by antigen affinity column.
Numéro d'accès P46821
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsMicrotubule-associated protein 1B, MAP-1B, MAP1B heavy chain, MAP1 light chain LC1, MAP1B
Contexte

Microtubule-associated protein 1B (MAP1B) is a ~270 kDa protein. Facilitates tyrosination of alpha-tubulin in neuronal microtubules. Phosphorylated MAP1B is required for proper microtubule dynamics and plays a role in the cytoskeletal changes that accompany neuronal differentiation and neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.

1. Cui, L. et al. (2020) JCI insight 5. PMID: 33268592
Note For research use only.
Images
  • Anti-Human MAP1B Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-MAP1B polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Mouse brain lysate

Reférences
Fiche technique
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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