

| Каталожный номер | HW426014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human MAP1B Polyclonal Antibody (HW426014) is a rabbit polyclonal antibody detecting MAP1B in ELISA, IHC, WB. Suitable for Rattus norvegicus, Mus musculus, and Human.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human MAP1B (Lys414-Glu567). | ||||||||
| Цель | MAP1B | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P46821 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Альтернативные названия | Microtubule-associated protein 1B, MAP-1B, MAP1B heavy chain, MAP1 light chain LC1, MAP1B | ||||||||
| Фон | Microtubule-associated protein 1B (MAP1B) is a ~270 kDa protein. Facilitates tyrosination of alpha-tubulin in neuronal microtubules. Phosphorylated MAP1B is required for proper microtubule dynamics and plays a role in the cytoskeletal changes that accompany neuronal differentiation and neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing. 1. Cui, L. et al. (2020) JCI insight 5. PMID: 33268592 | ||||||||
| Примечание | For research use only. |

Western blot analysis was performed using anti-MAP1B polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
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