Anti-Human Tau Recombinant Nanobody (SAA2138) (HY086253)

Name: Anti-Human Tau Recombinant Nanobody (SAA2138)
Brand: abinScience
SKU: HY086253
Price: 126 USD
Availability: InStock

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Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HY086253

Descripción

Anti-Human MAPT/Tau/PHF-tau Nanobody (SAA2138) [SAA2138] (HY086253) is a alpaca monoclonal antibody detecting PHF-tau in ELISA. Suitable for Human.

Reactividad de especies

Human

Aplicaciones

ELISA, FCM, IHC

Especie huésped

Alpaca

Clonalidad

Monoclonal

Isotipo

VHH-8His-Cys-tag

ID de clon

SAA2138

Objetivo

MAPT, MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau, TAU

Nivel de endotoxinas

< 10 EU/mg

Pureza

>95% as determined by SDS-PAGE.

Purificación

Purified by Nickel column

Número de acceso

P10636

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Microtubule-associated protein tau (MAPT) is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311

2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human MAPT/Tau/PHF-tau Nanobody (SAA2138).
Bioactivity

Detects recombinatn tau protein (Catalog No: HY086012) in indirect ELISA.