

| Numéro de catalogue | HA382014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human MARK4 Polyclonal Antibody (HA382014) is a rabbit polyclonal antibody detecting MARK4 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human MARK4 (Gly57-Lys370). | ||||||||
| Cible | MAP/microtubule affinity-regulating kinase 4, 2.7.11.1, MAP/microtubule affinity-regulating kinase-like 1, MARK4, KIAA1860, MARKL1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q96L34 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | MAP/microtubule affinity-regulating kinase 4 (MARK4) is a ~82 kDa protein. Serine/threonine-protein kinase. Phosphorylates the microtubule-associated protein MAPT/TAU. Also phosphorylates the microtubule-associated proteins MAP2 and MAP4. Involved in regulation of the microtubule network, causing reorganization of microtubules into bundles. Required for the initiation of axoneme extension during cilium assembly. 1. Trinczek, B. et al. (2004) The Journal of biological chemistry 279, 5915-23. PMID: 14594945 2. Schneider, A. et al. (2004) Journal of neurochemistry 88, 1114-26. PMID: 15009667 3. Li, L. et al. (2013) The Journal of biological chemistry 288, 703-8. PMID: 23184942 4. Gu, GJ. et al. (2013) Neuromolecular medicine 15, 458-69. PMID: 23666762 5. Rovina, D. et al. (2014) European journal of cell biology 93, 355-65. PMID: 25123532 6. Kuhns, S. et al. (2013) The Journal of cell biology 200, 505-22. PMID: 23400999 7. Li, X. et al. (2017) Nature communications 8, 15986. PMID: 28656979 | ||||||||
| Note | For research use only. |
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