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Anti-Human MARK4 Polyclonal Antibody (HA382014)

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概要
カタログ番号HA382014
説明
Anti-Human MARK4 Polyclonal Antibody (HA382014) is a rabbit polyclonal antibody detecting MARK4 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
種反応性Human, Mouse
アプリケーションELISA, IHC, WB
宿主種Rabbit
クローン性Polyclonal
アイソタイプIgG
免疫原 E. coli - derived recombinant Human MARK4 (Gly57-Lys370).
ターゲット MAP/microtubule affinity-regulating kinase 4, 2.7.11.1, MAP/microtubule affinity-regulating kinase-like 1, MARK4, KIAA1860, MARKL1
精製 Purified by antigen affinity column.
アクセッション番号 Q96L34
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

MAP/microtubule affinity-regulating kinase 4 (MARK4) is a ~82 kDa protein. Serine/threonine-protein kinase. Phosphorylates the microtubule-associated protein MAPT/TAU. Also phosphorylates the microtubule-associated proteins MAP2 and MAP4. Involved in regulation of the microtubule network, causing reorganization of microtubules into bundles. Required for the initiation of axoneme extension during cilium assembly.

1. Trinczek, B. et al. (2004) The Journal of biological chemistry 279, 5915-23. PMID: 14594945
2. Schneider, A. et al. (2004) Journal of neurochemistry 88, 1114-26. PMID: 15009667
3. Li, L. et al. (2013) The Journal of biological chemistry 288, 703-8. PMID: 23184942
4. Gu, GJ. et al. (2013) Neuromolecular medicine 15, 458-69. PMID: 23666762
5. Rovina, D. et al. (2014) European journal of cell biology 93, 355-65. PMID: 25123532
6. Kuhns, S. et al. (2013) The Journal of cell biology 200, 505-22. PMID: 23400999
7. Li, X. et al. (2017) Nature communications 8, 15986. PMID: 28656979
注意事項 For research use only.
イメージ
参考文献
Formula
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