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| カタログ番号 | HF785055 |
|---|---|
| 説明 |
Anti-Human MB Monoclonal Antibody (1A600) [1A600] (HF785055) is a mouse monoclonal antibody detecting Human MB in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, IHC, WB |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG |
| クローンID | 1A600 |
| 免疫原 | E. coli - derived recombinant human MB (Met1-Gly154). |
| ターゲット | Myoglobin, Nitrite reductase MB, EC:1.7.-.-, Pseudoperoxidase MB, EC:1.11.1.-, MB |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P02144 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Myoglobin (MB) is a ~17 kDa protein. Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand. Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide. Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity. 1. Olivé, M. et al. (2019) Nature communications 10, 1396. PMID: 30918256 2. Hofbauer, S. et al. (2022) The FEBS journal 289, 1105-1117. PMID: 34679218 3. Quesnelle, K. et al. (2020) Nitric oxide : biology and chemistry 104-105, 36-43. PMID: 32891753 |
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human MB Monoclonal Antibody (1A600)
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