

| Número de catálogo | HD132014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human MBLAC1 Polyclonal Antibody (HD132014) is a rabbit polyclonal antibody detecting MBLAC1. Suitable for Human.
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human MBLAC1 (Arg2-Arg236). | ||||||||
| Objetivo | EC:3.1.27.-, Endoribonuclease MBLAC1, MBLAC1, Metallo-beta-lactamase domain-containing protein 1 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | A4D2B0 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Metallo-beta-lactamase domain-containing protein 1 (MBLAC1) is a ~27 kDa protein. Endoribonuclease that catalyzes the hydrolysis of histone-coding pre-mRNA 3'-end. Involved in histone pre-mRNA processing during the S-phase of the cell cycle, which is required for entering/progressing through S-phase. Cleaves histone pre-mRNA at a major and a minor cleavage site after the 5'-ACCCA-3' and the 5'-ACCCACA-3' sequence, respectively, and located downstream of the stem-loop. May require the presence of the HDE element located at the histone pre-RNA 3'-end to avoid non-specific cleavage. 1. Pettinati, I. et al. (2018) eLife 7. PMID: 30507380 | ||||||||
| Nota | For research use only |
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