中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HA524014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human MCOLN2 Polyclonal Antibody (HA524014) is a rabbit polyclonal antibody detecting MCOLN2 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
||||||||
| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MCOLN2 (Asn87-Gln288). | ||||||||
| ターゲット | MCOLN2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8IZK6 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 別名 | Mucolipin-2, Transient receptor potential channel mucolipin 2, TRPML2, MCOLN2 | ||||||||
| 背景 | Mucolipin-2 (MCOLN2) is a ~65 kDa protein. Nonselective cation channel probably playing a role in the regulation of membrane trafficking events. Acts as a Ca(2+)-permeable cation channel with inwardly rectifying activity. May activate ARF6 and be involved in the trafficking of GPI-anchored cargo proteins to the cell surface via the ARF6-regulated recycling pathway. May play a role in immune processes. In adaptive immunity, TRPML2 and TRPML1 may play redundant roles in the function of the specialized lysosomes of B cells. 1. Curcio-Morelli, C. et al. (2010) Journal of cellular physiology 222, 328-35. PMID: 19885840 2. Lev, S. et al. (2010) The Journal of biological chemistry 285, 2771-82. PMID: 19940139 3. Karacsonyi, C. et al. (2007) Traffic (Copenhagen, Denmark) 8, 1404-14. PMID: 17662026 | ||||||||
| 注意事項 | For research use only. |
お問い合わせ
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
