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Anti-Human MCRS1 Polyclonal Antibody (HA075014)

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Vista general
Número de catálogoHA075014
Descripción
Anti-Human MCRS1 Polyclonal Antibody (HA075014) is a rabbit polyclonal antibody detecting MCRS1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human MCRS1 (Gln344-Gln462).
Objetivo MCRS1, INO80 complex subunit J, Microspherule protein 1, MCRS2, Cell cycle-regulated factor p78, INO80Q, MSP58, 58 kDa microspherule protein
Purificación Purified by antigen affinity column.
Número de acceso Q96EZ8
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Microspherule protein 1 (MCRS1) is a ~51 kDa protein. Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex, may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. Binds to G-quadruplex structures in mRNA.

1. Lin, DY. et al. (2002) The Journal of biological chemistry 277, 25446-56. PMID: 11948183
2. Cai, Y. et al. (2010) The Journal of biological chemistry 285, 4268-72. PMID: 20018852
3. Song, H. et al. (2004) Biochemical and biophysical research communications 316, 1116-23. PMID: 15044100
4. Davidovic, L. et al. (2006) Human molecular genetics 15, 1525-38. PMID: 16571602
5. Fawal, MA. et al. (2015) Developmental cell 33, 67-81. PMID: 25816988
6. Meunier, S. et al. (2011) Nature cell biology 13, 1406-14. PMID: 22081094
7. Meunier, S. et al. (2016) Cell cycle (Georgetown, Tex.) 15, 1779-86. PMID: 27192185
8. Yang, H. et al. (2019) Molecular biology of the cell 30, 1060-1068. PMID: 30785839
9. Laguillo-Diego, A. et al. (2023) Molecular biology of the cell 34, ar1. PMID: 36350698
Nota For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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