Anti-Human MCRS1 Polyclonal Antibody (HA075014)

Name: Anti-Human MCRS1 Polyclonal Antibody
Brand: abinScience
SKU: HA075014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HA075014

Description

Anti-Human MCRS1 Polyclonal Antibody (HA075014) is a rabbit polyclonal antibody detecting MCRS1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human MCRS1 (Gln344-Gln462).

Cible

MCRS1, INO80 complex subunit J, Microspherule protein 1, MCRS2, Cell cycle-regulated factor p78, INO80Q, MSP58, 58 kDa microspherule protein

Purification

Purified by antigen affinity column.

Numéro d'accès

Q96EZ8

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Microspherule protein 1 (MCRS1) is a ~51 kDa protein. Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex, may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. Binds to G-quadruplex structures in mRNA.

1. Lin, DY. et al. (2002) The Journal of biological chemistry 277, 25446-56. PMID: 11948183

2. Cai, Y. et al. (2010) The Journal of biological chemistry 285, 4268-72. PMID: 20018852

3. Song, H. et al. (2004) Biochemical and biophysical research communications 316, 1116-23. PMID: 15044100

4. Davidovic, L. et al. (2006) Human molecular genetics 15, 1525-38. PMID: 16571602

5. Fawal, MA. et al. (2015) Developmental cell 33, 67-81. PMID: 25816988

6. Meunier, S. et al. (2011) Nature cell biology 13, 1406-14. PMID: 22081094

7. Meunier, S. et al. (2016) Cell cycle (Georgetown, Tex.) 15, 1779-86. PMID: 27192185

8. Yang, H. et al. (2019) Molecular biology of the cell 30, 1060-1068. PMID: 30785839

9. Laguillo-Diego, A. et al. (2023) Molecular biology of the cell 34, ar1. PMID: 36350698

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human MCRS1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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