Anti-Human MCRS1 Polyclonal Antibody (HA075014)

Name: Anti-Human MCRS1 Polyclonal Antibody
Brand: abinScience
SKU: HA075014
Price: 168 USD
Availability: InStock

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Обзор

Каталожный номер

HA075014

Описание

Anti-Human MCRS1 Polyclonal Antibody (HA075014) is a rabbit polyclonal antibody detecting MCRS1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human MCRS1 (Gln344-Gln462).

Цель

MCRS1, INO80 complex subunit J, Microspherule protein 1, MCRS2, Cell cycle-regulated factor p78, INO80Q, MSP58, 58 kDa microspherule protein

Очистка

Purified by antigen affinity column.

Номер доступа

Q96EZ8

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Microspherule protein 1 (MCRS1) is a ~51 kDa protein. Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex, may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. Binds to G-quadruplex structures in mRNA.

1. Lin, DY. et al. (2002) The Journal of biological chemistry 277, 25446-56. PMID: 11948183

2. Cai, Y. et al. (2010) The Journal of biological chemistry 285, 4268-72. PMID: 20018852

3. Song, H. et al. (2004) Biochemical and biophysical research communications 316, 1116-23. PMID: 15044100

4. Davidovic, L. et al. (2006) Human molecular genetics 15, 1525-38. PMID: 16571602

5. Fawal, MA. et al. (2015) Developmental cell 33, 67-81. PMID: 25816988

6. Meunier, S. et al. (2011) Nature cell biology 13, 1406-14. PMID: 22081094

7. Meunier, S. et al. (2016) Cell cycle (Georgetown, Tex.) 15, 1779-86. PMID: 27192185

8. Yang, H. et al. (2019) Molecular biology of the cell 30, 1060-1068. PMID: 30785839

9. Laguillo-Diego, A. et al. (2023) Molecular biology of the cell 34, ar1. PMID: 36350698

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human MCRS1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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