

| Número de catálogo | HA896014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human MFSD2B Polyclonal Antibody (HA896014) is a rabbit polyclonal antibody detecting MFSD2B in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human MFSD2B (Ala2-Arg112). | ||||||||
| Objetivo | Sphingosine-1-phosphate transporter MFSD2B, Major facilitator superfamily domain-containing protein 2B, hMfsd2b, MFSD2B | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | A6NFX1 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Sphingosine-1-phosphate transporter MFSD2B is a ~53 kDa protein. Lipid transporter that specifically mediates export of sphingosine-1-phosphate in red blood cells and platelets. Sphingosine-1-phosphate is a signaling sphingolipid and its export from red blood cells into in the plasma is required for red blood cell morphology. Sphingosine-1-phosphate export from platelets is required for platelet aggregation and thrombus formation. Mediates the export of different sphingosine-1-phosphate (S1P) species, including S1P(d18:0) (sphinganine 1-phosphate), S1P (d18:1) (sphing-4-enine 1-phosphate) and S1P (d18:2) (sphinga-4E,14Z-dienine-1-phosphate) (Probable). Release of sphingosine-1-phosphate is facilitated by a proton gradient. 1. Vu, TM. et al. (2017) Nature 550, 524-528. PMID: 29045386 | ||||||||
| Nota | For research use only. |

Lane 1: Rat lung lysate
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