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| カタログ番号 | HA896014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human MFSD2B Polyclonal Antibody (HA896014) is a rabbit polyclonal antibody detecting MFSD2B in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MFSD2B (Ala2-Arg112). | ||||||||
| ターゲット | Sphingosine-1-phosphate transporter MFSD2B, Major facilitator superfamily domain-containing protein 2B, hMfsd2b, MFSD2B | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | A6NFX1 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Sphingosine-1-phosphate transporter MFSD2B is a ~53 kDa protein. Lipid transporter that specifically mediates export of sphingosine-1-phosphate in red blood cells and platelets. Sphingosine-1-phosphate is a signaling sphingolipid and its export from red blood cells into in the plasma is required for red blood cell morphology. Sphingosine-1-phosphate export from platelets is required for platelet aggregation and thrombus formation. Mediates the export of different sphingosine-1-phosphate (S1P) species, including S1P(d18:0) (sphinganine 1-phosphate), S1P (d18:1) (sphing-4-enine 1-phosphate) and S1P (d18:2) (sphinga-4E,14Z-dienine-1-phosphate) (Probable). Release of sphingosine-1-phosphate is facilitated by a proton gradient. 1. Vu, TM. et al. (2017) Nature 550, 524-528. PMID: 29045386 | ||||||||
| 注意事項 | For research use only. |
Lane 1: Rat lung lysate
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