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| カタログ番号 | HD501014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human MIEF1 Polyclonal Antibody (HD501014) is a rabbit polyclonal antibody detecting MIEF1. Suitable for Human.
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MIEF1 (Ala2-Ile70). | ||||||||
| ターゲット | AltMIEF1, AltMiD51, Alternative MIEF1 protein, MIEF1, MIEF1 microprotein, MIEF1-MP, Mitochondrial ribosome and complex I assembly factor AltMIEF1, alternative transcript upstream of MiD51 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | L0R8F8 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Mitochondrial ribosome and complex I assembly factor AltMIEF1 is a ~8 kDa protein. Assembly factor involved in the biogenesis of the mitochondrial-specific ribosomes (mitoribosomes). Specifically associates with intermediates of the mitochondrial ribosome large subunit (mt-LSU) and is required for proper ribosome assembly, possibly preventing premature association of the large and small ribosomal subunits. Thereby, indirectly regulates mitochondrial translation. It is also required for complete assembly of the mitochondrial respiratory chain complex I. May also function in DNM1L-mediated mitochondrial fission. 1. Brown, A. et al. (2017) Nature structural & molecular biology 24, 866-869. PMID: 28892042 2. Rathore, A. et al. (2018) Biochemistry 57, 5564-5575. PMID: 30215512 3. Dibley, MG. et al. (2020) Molecular & cellular proteomics : MCP 19, 65-77. PMID: 31666358 | ||||||||
| 注意事項 | For research use only |
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