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Anti-Human MIEF1 Polyclonal Antibody (HP379014)

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Número de catálogoHP379014
Descripción
Anti-Human MIEF1 Polyclonal Antibody (HP379014) is a rabbit polyclonal antibody detecting MIEF1 in ELISA, IHC, WB. Suitable for Human, Mouse, Pongo abelii, and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human MIEF1 (Ala119-Thr463).
Objetivo MID51, SMCR7-like protein, Mitochondrial dynamics protein MID51, MIEF1, Mitochondrial elongation factor 1, Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like, Mitochondrial dynamics protein of 51 kDa, SMCR7L
Purificación Purified by antigen affinity column.
Número de acceso Q9NQG6
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Mitochondrial dynamics protein MIEF1 is a ~51 kDa protein. Mitochondrial outer membrane protein which regulates mitochondrial fission/fusion dynamics. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP.

1. Zhao, J. et al. (2011) The EMBO journal 30, 2762-78. PMID: 21701560
2. Palmer, CS. et al. (2013) The Journal of biological chemistry 288, 27584-27593. PMID: 23921378
3. Charif, M. et al. (2021) Molecular neurodegeneration 16, 12. PMID: 33632269
Nota For research use only.
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Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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