

| Каталожный номер | HP379014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human MIEF1 Polyclonal Antibody (HP379014) is a rabbit polyclonal antibody detecting MIEF1 in ELISA, IHC, WB. Suitable for Human, Mouse, Pongo abelii, and Rat.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human MIEF1 (Ala119-Thr463). | ||||||||
| Цель | MID51, SMCR7-like protein, Mitochondrial dynamics protein MID51, MIEF1, Mitochondrial elongation factor 1, Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like, Mitochondrial dynamics protein of 51 kDa, SMCR7L | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q9NQG6 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Mitochondrial dynamics protein MIEF1 is a ~51 kDa protein. Mitochondrial outer membrane protein which regulates mitochondrial fission/fusion dynamics. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. 1. Zhao, J. et al. (2011) The EMBO journal 30, 2762-78. PMID: 21701560 2. Palmer, CS. et al. (2013) The Journal of biological chemistry 288, 27584-27593. PMID: 23921378 3. Charif, M. et al. (2021) Molecular neurodegeneration 16, 12. PMID: 33632269 | ||||||||
| Примечание | For research use only. |
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